(Goethe University Frankfurt) CRISPR/Cas enables the targeted deactivation of genes by cutting DNA at pre-determined sites. This is accomplished by providing the Cas enzyme with a genetic zip code. Using an entire library of zip codes, it is then possible to simultaneously probe multiple sites within the genome, for example to determine which genes are essential for cancer cell survival. This could revolutionize drug discovery.
from EurekAlert! - Technology, Engineering and Computer Science https://ift.tt/2TRQxir
Thursday, March 21, 2019
CRISPR/Cas libraries open new avenues in cancer research
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